1) alkyl rhodanate
硫氰酸烷基酯
3) butyl rhodanate
硫氰酸丁酯;丁基硫氰
4) alkyl isocyanate
异氰酸烷基酯
5) aralkyl novolac cyanate ester
芳烷基氰酸酯
6) glycosyl isothiocyanate
糖基异硫氰酸酯
1.
Fifteen target compounds were synthesized with the following three steps: amino acids were protected to form carbobenzoxyamino acid methyl esters, the carbobenzoxyamino acid methyl esters reacted with hydrazine to give carbobenzoxy amino acid hydrazides, and treatment of the carbobenzoxy amino acid hydrazides with glycosyl isothiocyanates afforded 3a～3o in 65%～86% yields.
通过对5种氨基酸酯化和氨基保护得到苄氧羰基氨基酸甲酯,经肼解制备苄氧羰基氨基酸酰肼,然后分别与3种不同的糖基异硫氰酸酯反应,制备了相应的目标化合物15个,且产率均在60%以上。
2.
The reaction of 2 with glycosyl isothiocyanates 3～5 gave the novel compounds, N-glycosyl-N'-amido thioureas 6～8.
以L-α-氨基酸为起始原料,经酯化、氨基保护、肼解制得N-对甲苯磺酰基-L-α-氨基酸酰肼2,再与糖基异硫氰酸酯3～5反应,得到9种新型N-糖基-N'-酰氨基硫脲6～8,然后在Hg(OAc)2/EtOH条件下关环,合成了一系列新的2-对甲苯磺酰氨基烃基-5-糖氨基-1,3,4-噁二唑类化合物9～11。
3.
The glycosyl isothiocyanates 1a～1c reacted with anhydrous hydrazine gave N-glycosyl- N'-aminothioureas 2a～2c, which then reacted further with 6-substituted-3-formylchromones 3a～3d to give a series of new N-glycosyl-N′-6-substitutedchromon-3-ylmethylideneaminothioureas 4a～4d, 5a～5d, 6a～ 6d.
糖基异硫氰酸酯(1a～1c)与无水肼反应,生成糖基氨基硫脲2a～2c,再与6-取代-3-甲酰基色酮3a～3d反应,得到一系列新的N-糖基-N′-(6-取代色酮-3-基-亚甲氨基)硫脲类化合物4a～4d,5a～5d,6a～6d。
补充资料：硫氰酸
可能有两种同分异构体，一为硫氰酸H-S-C≡N，一为异硫氰酸H-N=C=S。游离酸还没有分离出来。大多数硫氰酸盐都溶于水。SCN-离子是一个很好的配位体。SCN-离子一个特殊灵敏的反应是与Fe3+形成多种红色络合物。因此硫氰酸钾或硫氰酸铵常用作检验Fe3+的试剂。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条