It is indicated that GABA, which is the major inhibitory neurotransmitter in the CNS, plays a role in the effect on the hypoxia-induced increase of epilepsy susceptibility.

Objective To investigate the changes of interleukin-2 (IL-2) and its soluble receptor (sIL-2R),and effects on convulsion in genetically epilepsy-prone rat(P77PMC).

Objective To investigate the changes and role of nitric oxide (NO)and nitric oxide synthase(NOS) in convulsions of genetically epilepsy-prone rat(P77PMC);Methods 35 rats with convulsion scores30-40 were randomly divided into 7 groups(A-G) respectively ,A -control ,G were pretreated with inhibitor of NOS ( N-nitro- arginine methyl ester, L-NAME) .

Effect of hypoxic brain injury on seizure susceptibility and PSD-95 expression in rats;

The expression of proto-oncogen c-jun and the relationship with the proliferation of astrocytes, as well as the expression of glia fibrillary acidic protein (GFAP) were studied by the technique of immunocytochemistry, in the period of long-lasting enhanced seizure susceptibility induced by kainic acid(KA).

To study a role of dynorphin A(1 8)(DYN A(1 8)) in ventral hippocampus during induction of enhanced seizure susceptibility, an acute model as human temporal lobe epilepsy was made by kainic acid (KA) causing seizure episode in the rats.

The role of the change of Bcl-2 expression in the long-lasting enhancement of seizure susceptibility induced by kainic acid (KA) was investigated in the present study.

Objective To study the relationship o f the mossy fiber sprouting in the hippocampal dentate gyrus and the formation of epileptic seizure susceptibility.