Objective To explore the mutation of voltage-gated sodium channel β1 subunit(SCN1B)gene in Chinese Han families with generalized epilepsy with febrile seizures plus(GEFS+).

Deglycosylation altered the gating properties of rNav1.3:glycosylation/deglycosylation homeostasis probably complicates the functional regulation of voltage-gated sodium channel;

Effects of arachidonic acid on the voltage-gated sodium channel of rabbit cardiac ventricular myocytes

Voltage-gated sodium channels Nav1.5 functionally expressed in ovarian caner

In this paper, using the electriphysiological techniques of single cell and brain slices, we studied the effects of ALA on voltage-gated sodium channels in acutely dissociated rat hippocampal CA1 neurons, and the changes of synaptic plasticity and synaptic transmission induced by ALA.

Furthermore,the external calcium was found to influx mainly through N-type calcium channels and voltage-gated sodium channels.

Distribution of SCN1B single nucleotide polymorphism in idiopathic epilepsy patients and its association with electroencephalogram

The morphologic changes were observed under a light microscope and a transmission electron microscope;The growth inhibition of cells was assayed by methyl-tetrazolium(MTT)assay;The feature of cell death was studied by Hoechst33342/PI staining and the mRNA expressions of Na-K-ATPase β1-subunit,VE-Cadherin,P120-catenin 1A and P120-catenin 3A were assayed by reverse transcription PCR(RT-PCR).