2) Notch signal
Notch信号
1.
The proliferation and apoptosis of multiple myeloma (MM) cells were regulated by bone marrow microenvironments in which Notch signal plays important role in mediating cell-cell communication.
Notch信号是骨髓中细胞与细胞之间通讯的主要信号通路之一 ,它对多发性骨髓瘤细胞的调节作用目前并不清楚。
2.
Active Notch signal inhibits the differentiation of HSCs while promotes their expansion,suggesting that ex vivo expansion of hematopoietic progenitor cells could be enhanced by manipulating Notch signal pathway.
Notch受体和配体在造血系统中广泛存在,活化的Notch信号可抑制造血祖细胞的分化而促进其扩增,提示可以通过Notch信号途径实现对造血祖细胞的扩增。
3.
Notch signal is one of the main direct action signal path between cell and cell,and is key point to determine cell fate of organisma multicellularis.
Notch信号是细胞与细胞之间直接作用的主要信号通路之一,并对多细胞生物中细胞命运的决定起关键作用。
3) Notch signaling
Notch信号
1.
Relationship between the Notch signaling and cardiovascular development;
Notch信号通路与心血管发育的关系
2.
Hypoxia-responsive Notch signaling suppressing protein regulates the in vivo growth of CT26 colon carcinoma cells in mice
具有缺氧反应性的Notch信号抑制蛋白调节鼠结肠癌细胞的体内生长
3.
Notch signaling pathway is an evolutionarily highly conserved mechanism for cell-cell communication, which controls differentiation and proliferation, and plays an important role in embryogenesis and many types of cell fate determination.
Notch信号是一个在进化中高度保守的反映细胞间通讯机制的通路,它调控细胞的分化和增殖,在胚胎发育和细胞命运的决定中发挥重要的作用。
4) Notch signal pathway
Notch信号通路
1.
The Notch signal pathway is a conservative mechanism between cells,which keep the balance of cell proliferation,differentiation and apoptosis,and enlarge and rigidificate molecule difference between cells and determine the cell differentiation.
Notch信号通路作为一种进化上相对保守的细胞相互作用机制,维持着细胞增殖、分化、凋亡之间的平衡,其能够扩大并固化相邻细胞之间的分子差异,对细胞分化命运起决定性作用。
2.
It s pathogenesis is comparatively complicated and recently is focused on abnormality in early genetics,interaction between hemopoietic microenvironment and myeloma cells,NF-κB and Notch signal pathways and drug resistance.
多发性骨髓瘤(mu ltip le myelom a,MM)是一种恶性增殖性疾病,其发病机制十分复杂,近年集中在早期遗传学异常、造血微环境与骨髓瘤细胞的相互作用、NF-κB和Notch信号通路、MM耐药机制几方面,形成了以针对信号通路和骨髓微环境治疗为主的综合治疗框架。
3.
To study the role of Notch signal pathway in the proliferation and differentiation of NSCs.
Notch信号通路对于维持体外培养的神经干细胞增殖有重要的作用。
5) Notch signaling pathway
Notch信号途径
1.
Objective To construct and identify a reporter plasmid for analyses of the mechanism of Notch signaling pathway in human cervical carcinoma cells.
目的构建并鉴定一种检测细胞内活化的Notch信号途径的报告基因质粒,用于研究该途径在宫颈癌细胞中的作用机制。
2.
The Notch signaling pathway plays a pivotal role in cell fate specification in development by mediating cell-cell interaction and is conserved during evolution from worm through man.
Notch信号途径是在发育过程中通过介导细胞间的相互作用而调控细胞分化方向的重要信号途径，在进化中高度保守。
3.
The Notch signaling pathway is an evolutionarily conserved mechanism that is involved in the regulation of many biological functions,such as apoptosis,cell proliferation,differentiation and lineage decisions during embryonic development,and homeostasis of adult self-renewing organs.
Notch信号途径是一条在进化上高度保守的通路,广泛存在于多种生物体内,主要调控细胞的增殖与分化。
补充资料：[3-(aminosulfonyl)-4-chloro-N-(2.3-dihydro-2-methyl-1H-indol-1-yl)benzamide]
分子式：C16H16ClN3O3S
分子量：365.5
CAS号：26807-65-8
性质：暂无
制备方法：暂无
用途：用于轻、中度原发性高血压。
分子量：365.5
CAS号：26807-65-8
性质：暂无
制备方法：暂无
用途：用于轻、中度原发性高血压。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条