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1)  ApoE and LDLR gene knockout mice
ApoE和LDLR基因敲除小鼠
1.
【Results】 In animals of high-fat diet,compared with ApoE and LDLR gene knockout mice fed with a normal mouse chow,AS plaques are significantly enlagered with a large number of inflammatory cells and decreased of matrix fiberous component and thinner in fibrous caps with a changed shape and deposited a large amount of neutral lipid drops in plaque.
结论高脂饮食可加重ApoE和LDLR基因敲除小鼠AS斑块形成和Mac-3表达及炎症细胞增加,MMPs水平亦相应增加,其病变呈现出不稳定性斑块特征。
2)  ApoE gene knockout mice
ApoE基因敲除小鼠
1.
Effects of liver X receptor agonist on the expressions of C-reactive protein and CD40 ligand and contents of smooth muscle cells in the aorta of ApoE gene knockout mice
肝X受体激动剂对ApoE基因敲除小鼠主动脉壁C-反应蛋白和CD40配体表达及平滑肌细胞含量的影响
2.
Effects of celastrol on the expression of CD40 ligand and number of macrophages and smooth muscle cells in the atherosclerotic plaques of ApoE gene knockout mice
南蛇藤素对ApoE基因敲除小鼠主动脉粥样硬化斑块内CD40配体表达、巨噬细胞和平滑肌细胞数量的影响
3)  ApoE/LDLR-DKO
ApoE、LDLR双基因缺失(apoE-/-/LDLR-/-)小鼠
4)  ApoE gene knockout mice
ApoE基因敲除鼠
5)  ApoE-Knock Out
ApoE-基因敲除鼠
6)  ApoE and LDLR double knockout mice
apoE、LDLR双基因缺失小鼠
补充资料:[3-(aminosulfonyl)-4-chloro-N-(2.3-dihydro-2-methyl-1H-indol-1-yl)benzamide]
分子式:C16H16ClN3O3S
分子量:365.5
CAS号:26807-65-8

性质:暂无

制备方法:暂无

用途:用于轻、中度原发性高血压。

说明:补充资料仅用于学习参考,请勿用于其它任何用途。
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