1.
There are many big things involved in this.
这里面牵扯许多大问题。
2.
At least medi-cal bills were not a major concern;
至少医疗费不是大问题；
3.
The thinness of the wire was a great problem.
电线很细是个大问题。
4.
That's not a big problem.
这不是什么大问题。
5.
We've run up against a big problem.
我们碰到了一个大问题。
6.
There's nothing seriously the matter with your stomach.
胃没有什么大问题，
7.
The experiment went disastrously wrong, ie progressed in an unexpected way with very unpleasant results.
这个试验出了大问题。
8.
Snacking can also be a big problem.
小吃也会是一个大问题。
9.
A great problem confronted them.
他们面临一个大问题。
10.
There should be collective leadership in settling major issues.
集体领导解决重大问题；
11.
The air pollution has become a big problem.
空气污染已成为大问题。
12.
Ownership is an important theoretical and practical problem.
所有制问题是重大的理论问题及现实问题。
13.
The Problem of No Questions:A Vital Issue in the University Education
没有问题的问题——大学教育中不容忽视的问题
14.
The difference was not only over the special economic zones but also over the bigger issues,
不只是经济特区问题，还有更大的问题，
15.
54. Freshwater issues are a concern for all.
54. 淡水问题是大家都关心的问题。
16.
"Basically , NO Pro*em " means BIG pro*em.
基本上，没有问题＂意味着有极大的问题。
17.
a subject scanted in the mass media
大众传播所轻视的问题,大众传播不大提的问题
18.
The Ambassador's wife went on asking questions,
大使夫人继续提出问题，