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1)  Cardiomyocyte apoptosis
心肌细胞凋亡
1.
The effect of losartan on cardiomyocyte apoptosis and bcl-2, bax and p53 gene expression induced by ischemia and reperfusion in rats;
氯沙坦对大鼠心肌缺血再灌注诱导心肌细胞凋亡及对bcl-2,bax和p53基因表达的影响
2.
Effect of thyroid function on cardiomyocyte apoptosis in rats;
大鼠甲状腺功能状态对心肌细胞凋亡的影响
3.
Influence of Jiawei Danshen decoction on cardiomyocyte apoptosis caused by myocardial ischemia reperfusion in rabbits with blood stasis syndrome
加味丹参饮对血瘀证家兔缺血再灌注损伤心肌细胞凋亡的影响
2)  Myocardial apoptosis
心肌细胞凋亡
1.
Development of myocardial apoptosis during physical training;
运动训练中心肌细胞凋亡的研究进展
2.
The effect of Beating Heart Surgery On Myocardial apoptosis
不停跳心内直视手术对心肌细胞凋亡的影响
3.
Thomas Ⅱ solution supplemented with diazoxide(DZ)and fructose-1,6-diphosphate(FDP)on myocardial apoptosis in cryopreserved rat hearts.
提要:目的观察含二氮嗪(DZ)与1,6-二磷酸果糖(FDP)心麻痹液对冷保存大鼠心脏心肌细胞凋亡的影响。
3)  myocardial cell apoptosis
心肌细胞凋亡
1.
Relation of myocardial cell apoptosis in the junctional zone induced by ischemia reperfusion and activation of Caspase-3 and expression of p53, bcl-2;
缺血再灌注诱导交界区心肌细胞凋亡与Caspase-3的活化及p53、bcl-2基因表达的关系
2.
ObjectiveTo study the possible mechanism of anti-myocardial cell apoptosis of astragaloside induced by adriamycin (ADR).
目的探讨黄芪甲甙(简称黄芪)抗阿霉素所致心肌细胞凋亡的可能机制。
3.
Objective To investigate effects of compound danshen drop pills (DSP) with fosinopril on myocardial cell apoptosis in rats with spontaneously hypertension.
目的探讨复方丹参滴丸(DSP)及其与福辛普利联用对自发性高血压大鼠(SHRs)心肌细胞凋亡的影响。
4)  cardiac myocyte apoptosis
心肌细胞凋亡
1.
A clinical study on cardiac myocyte apoptosis in beating heart mitral valve replacement;
心脏跳动中二尖瓣置换术心肌细胞凋亡的临床研究
2.
Aim:To discuss the effects of restrained stress on cardiac myocyte apoptosis of rats in the whole body,and the effect of anti-stress-induced cardiac myocyte injury treated by Chinese herbs Yixinning.
目的 :探讨束缚应激对大鼠心肌细胞凋亡的影响及中药颐心宁抗应激性心肌损伤的作用。
5)  Myocyte apoptosis
心肌细胞凋亡
1.
Myocyte apoptosis and the protein expression of bax and bcl-2 genes were detected by random digoxin labeling and immunohistochemistry.
目的 探讨丹参对大鼠急性心肌缺血再灌注时心肌细胞凋亡及凋亡相关基因表达的影响。
2.
Objective : To investigate the effect of probucol on ischemia/reperfusion -induced myocyte apoptosis, the total activity of serum superoxide dismuase (T-SOD), and serum concentration of malondialdehyde(MDA) in New Zealand White rabbits and its possible mechanism.
目的:探讨普罗布考对新西兰白兔缺血/再灌注损伤模型心肌细胞凋亡、血清超氧化物歧化酶活性和丙二醛浓度的影响及其关系。
3.
OBJECTIVE: Myocyte apoptosis resulted from ischemia/reperfusion (I/R) have been demonstrated in animal models as well as in patients with acute myocardial infarction, and oxidative stress have been found to play a critical role in I/R-mediated myocyte apoptosis.
目的:大量的实验显示心肌细胞凋亡是缺血/再灌注损伤的病理特征之一,与再灌注后心肌重构、心律失常、心肌顿抑/心肌冬眠和心力衰竭有关。
6)  myocardial cellular apoptosis
心肌细胞凋亡
1.
Objective:To explore the intervention of Danshenyin decoction on myocardial cellular apoptosis and expressions of Bcl-2,Bax in acute experimental ischemic myocardium.
目的:观察丹参饮对心肌细胞凋亡与相关蛋白表达干预作用。
2.
Objective To explore the intervention effect of activating blood and removing stasis decoctions on myocardial cellular apoptosis and expression of Bcl-2 and Bax in acute experimental ischemic myocardium.
目的观察两首活血化瘀方对心肌细胞凋亡与相关蛋白表达干预的作用。
3.
Objective To explore the effect of Xuefuzhuyu decoction on myocardial cellular apoptosis and expressions of Bcl-2 and Bax in acute experimental myocardial ischemia.
目的观察血府逐瘀汤对心肌细胞凋亡与相关蛋白表达干预的作用。
补充资料:细胞凋亡
分子式:
CAS号:

性质:是细胞的一种不同于坏死的死亡方式,是由基因控制的细胞自我消亡过程,是一连串精确的生化变化的结果,不像坏死是意外事件使细胞受损伤的消极结果,其发生为机体维持衡态所需,因而有积极的生物学意义。细胞凋谢开始时,染色质凝集、分块,位于核膜上,细胞质凝缩,核及细胞的外形都有卷曲,几分钟后,核断裂,细胞表面有柄状突起,最后产生有膜包裹的细胞凋谢体,随即被周围的细胞所吞噬。这与坏死细胞完全不同,后者是不成形的染色质块,膨胀的细胞器,以及混浊的线粒体。细胞凋谢的另一特征是可能有新的蛋白质合成,可能是为启动细胞凋谢所需。程序化细胞死亡(programmed cell death;PCD)概念与细胞凋亡起于相同时期,常被认为有相关或甚至等同的意义。但是,尽管两者都不同于细胞坏死,即不伴有发炎和细胞崩溃及内含物的释放,都是由基因指导的细胞自我消亡,具有明确的生物学功能。但二者不能等同起来。PCD的细胞死亡是按照一定程序发生的变化。也有核固缩和胞质缩合等细胞凋亡现象。

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