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1)  topoisomerases
拓扑异构酶类
2)  DNA topoisomerases
DNA拓扑异构酶类
3)  topoisomerase
拓扑异构酶
1.
Identification of common species of dermatophytes by PCR-RFLP techniques targeting topoisomerase II gene;
拓扑异构酶II基因区PCR-RFLP法鉴别常见皮肤癣菌
2.
Investigation on the Raw Materials Plants Resources of Topoisomerase Inhibitor in Kunyu Mountain
昆嵛山拓扑异构酶抑制剂原料植物资源调查
3.
Objective To study the roles of DNA topoisomerases(Topo) in ovarian cancer TPT-resistant cells.
目的探讨DNA拓扑异构酶(Topoisomerase,Topo)在卵巢癌拓扑替康(TPT)耐药细胞A2780/TPT中的作用。
4)  topoisomerase Ⅱ
拓扑异构酶
1.
Objective To detect the expression of p53、multidrug resistance gene1(mdr1) gene,glutathione S-transferase(GST-π),lung resistance protein(LRP),topoisomerase Ⅱ(Topo Ⅱ),and to evaluate their relationship with staging and classification of cancer,differentiation degree,lymphatic metastasis,and tumor invasion.
目的检测食管癌组织中P53、多药耐药基因(mu ltidrug resistance gene1,MDR1)及其编码产物P-糖蛋白(p-glycoprote in,P-gp)、肺耐药蛋白(lung resistance prote in,LRP)、谷胱甘肽S-转移酶(glutath ione S-transferase,GST-π)、拓扑异构酶(topoisom eraseⅡ,TopoⅡ)的表达水平,探讨其与临床分期、分化程度、淋巴结转移、肿瘤浸润深度及病理分型的关系。
5)  topoiso-merase I
拓扑异构化酶
6)  DNA topoisomerase
拓扑异构酶Ⅰ
1.
Camptothecin (CPT) compounds specifically acting on DNA topoisomerase Ⅰ (TopoI) are promising antitumor drugs, and have been widely used in the clinic.
喜树碱类抗肿瘤药物是DNA拓扑异构酶Ⅰ(1bpoisomerase I,TopoI)的特异性抑制剂,目前已广泛应用于临床。
2.
Camptothecin(CPT)compounds are specific inhibitors of DNA topoisomerase Ⅰ(TopoⅠ)which have been widely used in the clinic.
喜树碱类抗肿瘤药物是临床广泛使用的DNA拓扑异构酶Ⅰ (topoisomeraseⅠ ,TopoⅠ )的特异性抑制剂。
3.
Camptothecin(CPT)compounds are specific inhibitors o f DNA topoisomerase Ⅰ(TopoI)and have been widely used in the clinic.
喜树碱类抗肿瘤药物是临床广泛使用的经典的作用于DNA拓扑异构酶Ⅰ的特异性抑制剂。
补充资料:DNA拓扑异构酶
分子式:
CAS号:

性质:在DNA复制期间和子DNA分子分离时催化DNA链瞬间时断裂的一种酶。

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