1) Multidrug resistance 1a
多药耐药基因1a
2) MDR-1
多耐药基因
3) Multi-drug resistance gene
多药耐药基因
1.
Relationship between multi-drug resistance gene polymorphism and blood concentration of ciclosporin in renal transplantation patients;
肾移植中环孢素的血药浓度与多药耐药基因多态性的关系
2.
Relationship between multi-drug resistance gene MDR1 and NF-kappa B in human drug-resistance erythroleukemia cells
白血病耐药细胞中多药耐药基因MDR1与核转录因子κB的关系
3.
Relationship between multi-drug resistance gene genetic polymorphism and blood concentration of tacrolimus in liver transplant patients
肝移植中他克莫司的血药浓度与多药耐药基因多态性的关系
4) multidrug resistance gene
多药耐药基因
1.
Study on multidrug resistance gene expression between peripheral blood lymphocytes and tumor cells in hepatocellular carcinoma;
肝癌外周血淋巴细胞和肿瘤细胞多药耐药基因表达的研究
2.
Relationship between the expression and distribution of multidrug resistance gene and clinical effect in lupus nephritis;
狼疮性肾炎多药耐药基因的表达分布与临床疗效关系的探讨
3.
Clinical significance of multidrug resistance gene expression in advanced gastric cancer;
进展期胃癌多药耐药基因表达的临床意义
5) MDR1
多药耐药基因1
1.
CYP3A5 and MDR1 gene polymorphisms is associated with pharmacokinetic variation of tacrolimus in renal transplant patients;
细胞色素P450 3A5和多药耐药基因1基因多态性在肾移植患者他克莫司血药浓度监测中的应用
2.
Objective To investigate the therapeutic efficacy and the possible action mechanisms of the recombinant adenovirus vector carrying antisense multidrug resistance gene 1(mdr1)targeting the reverse of α-fetoprotein(AFP+)positive MDR of HepG2R cells.
目的探讨携带多药耐药基因1(multidrug resistance gene1,mdr1)反义RNA重组腺病毒载体靶向逆转甲胎蛋白阳性(AFP+)的肝癌多药耐药细胞HepG2R的疗效及作用机制。
3.
Results The influences of independent variables on dependent variables in order of size were MDR1 3435(1)>MDR1 1236(1)>CYP3A5(2)>LDL>DBIL>Age>TC>HDL>L.
结果9个自变量对因变量的影响从大到小依次为多药耐药基因1(MDR1)3435(1)、MDR11236(1)、细胞色素酶P450-3A5(CYP3A5)(2)、低密度脂蛋白胆固醇(LDL)、直接胆红素(DBIL)、年龄、总胆固醇(CHOL)、高密度脂蛋白胆固醇(HDL)、淋巴细胞(L);对方程内各自变量单独检验,CYP3A5(2)、MDR1 3435(1)、MDR1 1236(1)、DBIL、年龄、LDL、HDL对因变量有显著影响。
6) multidrug resistant gene
多药耐药基因
1.
Effect of fetal liver AFT024 cells on multidrug resistant gene 1 transfection efficiency and in vitro expansion of CD34~+ cells derived from umbilical cord blood;
胎肝AFT024细胞对脐血CD34~+细胞体外扩增及多药耐药基因转染的影响
2.
Multidrug resistant gene mdr1 expression in oral squamous cell carcinoma before and after chemotherapy;
口腔鳞癌化疗前后多药耐药基因表达变化的分析研究
3.
Purpose To determine the relationship between C3435T,a single nucleotide polymorphism (SNP) in exon 26 of the human multidrug resistant gene (MDR1) and cyclosporine (CsA) pharmacokinetic (PK) parameters among healthy Chinese volunteers.
的 探讨多药耐药基因 (MDR1 ) 2 6外显子C3435T多态性与环孢素A(CsA)药动学特性间的关系。
补充资料：安眠药、镇静药
安眠药、镇静药
HyPnoties，Sedatives
an而anyao、Zhenjingyao安眠药、镇静药Hypnotics，SedativeS蔡月刚上海医药工业研究院L概述··············……2.主要的安眠、镇静药2.1.醇类·········.··..……2.2.环状酞胺类·····……2.3.酸脉类···········……2.4.氨基甲酸醋类·”一2.5.苯二氮草类····……2.6.吩唯嗦类·······································……312.7.乙醇胺类·······································……312.8.二苯甲烷类······················，····……，··……312.9.叱咯酮类·······································……312.10.巴比妥类·······································……31参考文献················································……咒墓本参考文献··········································……33q八成J gJ广n占亡户nt了0‘2，﹄Q乙2，︺21.概述 安眠药又称催眠药，是一类对中枢神经系统产生抑制作用的药物，在应用适当剂量时，这种抑制作用能导致睡眠(见神经调节荆)。在较小剂量时可使紧张、焦虑和兴奋不安的患者安静下来，有思睡状态，但又不致入睡，这时就称为镇静药。大剂量的安眠药还可产生麻醉。实际上安眠药和镇静药并无明显的界限，而只有量的差别。有些类别的安眠药如使用特大剂量时还可引起昏迷和可能死亡。 失眠是一种不能得到良好睡眠的生理现象，表现为入睡困难、早醒、夜不成寐，即使暂时入睡，但醒后常感头晕脑胀、腰酸背痛，并无正常睡眠醒后的清新之感等等，总之，失眠患者常不能从睡眠中完全消除疲劳。失眠常与下列原因有关;如焦虑、心理障碍、精神上的打击、噪声(见噪声)和工作过度等等。长期失眠可造成中枢神经细胞功能失调，适当应用安眠药是必要的。 理想的安眠药应能使病人安然入睡，而在醒后不遗留任何不适感，并有正常工作的能力。一般患有失眠症的人，服用安眠药后即能获得类似生理性的睡眠，但多数醒后有精神萎靡不振等不良反应。如由于某些躯体疾病，如关节炎、神经痛和心绞痛等引起的失眠，则需首先进行病因性治疗口长期应用安眠药可产生依赖性和成瘾性。 目前对于睡眠发生的机理尚不清楚，但经过多年的努力，已经深入了一步。
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参考词条