The results show that,in static state,hesepridin can be cumulated on the D296 resin and eluted with CuCl2-MeoH mixture,resulting in the formation of a hesperidin-Cu complex.

) ofhesperidin and hesperidin-with zinc complex,proves that the scavenying capacity of free radicalof hesperidin-with zinc complex is stronger than that of hesperidin.

Hesperidin can possess better biological activity after having coordinated with Cu2+,and rare reports can be reached about the crystallization of hesperidin-Cu.

Quantitative determination of aurantiamarin in Rongjin tablets by HPLC;

Determination of peoniflorin,naringin,aurantiamarin,neohesperidin,and ammonium glycyrrhizinate in Sini Powder by HPLC-"internal standard" multi-control method;

METHODS The rhizoma atractylodix macrocephalae and fructus crataegi in Xiaoer jianpi oral liquid were identified by TLC,the content of aurantiamarin in Xiaoer jianpi oral liquid was determined by HPLC.